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Junior Investigator Research Award

Grants to Newly Independent Investigators
to Support A Wide Range of Epilepsy-Related Research

Agency Type:

Foundation / Corporation

Funding Source:

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Epilepsy Foundation and the American Epilepsy Society

LOI Date:


Deadline Date:

01/31/19 5:00 PM


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Grants of up to $50,000 to recently independent researchers with an M.D., Ph.D., Sc.D., PharmD, RN, or equivalent degree to support research in an area related to epilepsy. An LOI must be submitted prior to the full application. Funding is intended for basic, translational, or clinical research studies of disease mechanisms or treatments, epidemiologic or behavioral studies, the development of new technologies, and health services and outcomes research. The award is meant to facilitate successful competition for subsequent longer-term support from the NIH or other sources.

Evaluation Criteria include:
- Significance: Does the proposed project address an important problem or crucial barrier in the epilepsy field, for example as framed by the 2014 NINDS Benchmarks for Epilepsy Research or the Institute of Medicine 2012 research recommendations around public health for epilepsy research?
- Applicant: Does the applicant have appropriate experience and training and potential for further success as an independent researcher? Are the collaborators and other researchers well suited to the project?
- Innovation: Does the application challenge and seek to shift current research or clinical practice paradigms by utilizing novel theoretical concepts, approaches or methodologies, instrumentation, or interventions? What is the strength of the scientific premise, i.e. the quality and strength of the prior research used as a basis for the proposed research question? Please refer to NIH guidelines for more clarification.
- Approach: Is the research project well-conceived with rigor in experimental design, methodology, analysis, interpretation, and reporting of results? Does it include clear hypotheses and potential alternative outcomes? Does it consider key biological variables like gender and include authentication of key biological and/or chemical resources, if appropriate, as defined by the NIH guidelines on rigor & transparency? Are the overall strategy, methodology, and analyses well-reasoned and appropriate to accomplish the specific aims of the project? Does the proposed research include a data-sharing plan? While not required, it can provide added value to the work.
- Environment: Are the institutional support, equipment, and other physical resources available to the applicant adequate for the proposed project as an independent primary investigator rather than a mentee in another laboratory?
Will the project benefit from unique features of the scientific environment, subject populations, or collaborative arrangements?

Allowable use of the grant includes: salary for the principal investigator and for scientific personnel directly engaged in the research project; consumable supplies, disposables, and animals necessary to fulfill the project’s specific aims; and travel related to the conduct of the research or for the purpose of presenting the results of the research at appropriate scientific or medical meetings. Travel must be conducted during the funding period.

GrantWatch ID#:

GrantWatch ID#: 184887

Number of Grants:

The number of awards granted each year is contingent upon available funds.

Estimated Size of Grant:

This award provides up to $50,000 for one year to support the direct costs of research, as well as complimentary membership and registration to the AES Annual Meeting for one year.

Additional Eligibility Criteria:

Applicants must:
-Hold an M.D., Ph.D., Sc.D., PharmD, RN, or equivalent degree.
-Have an academic appointment at the level of Assistant Professor or equivalent at a university, medical school, research institution, or medical center. Researchers with other early faculty appointments (such as Instructor, Adjunct Track, etc.) may apply but are strongly encouraged to provide a letter of support from their department chair.
- Not currently hold or have previously received a larger, multi-year award for independent research, such as an NIH R01 grant.
-Have a defined research plan and access to institutional resources to conduct the proposed project.
- Have not previously been awarded an American Epilepsy Society Award or Research Grant.
- Not be listed as the primary mentor on a proposal for a mentored research award by AES. The policy for AES awards is to allow only one proposal to be considered each year from any given laboratory.
- Physician applicants whose research will involve patient care or direct involvement with patients must have completed all residency training and be licensed to practice medicine at their institution.
-U.S. citizenship is not required; however, all research must be conducted in the U.S.
-Applications are encouraged from women, members of minority groups, and people with  disabilities.

Grant funds MAY NOT be used for: indirect costs or institutional overhead; purchase of permanent equipment that exceeds 10% of the budget; payment of salaries of collaborators at other institutions; or membership dues, subscriptions, books, or journals.

Postdoctoral associates, postdoctoral fellows, clinical fellows, and researchers appointed to the position of associate professor or higher are not eligible.

Pre-Application Information:

Letter of Intent: Due by December 20, 2018

Only applicants who have submitted a LOI and receive approval are eligible to submit a full grant application. LOI will be evaluated solely for the applicant’s eligibility for the grant mechanism.

- November 1, 2018 by 5:00 PM ET: Concise LOI submission opens through proposalCENTRAL
- December 20, 2018: Concise LOI submission deadline
- January 8, 2019: Applicants invited to submit full proposals, following eligibility screen
- January 31, 2019: Full proposals due
- May 2019: Award notifications sent out
- July 1, 2019: Earliest start date. May be delayed up to 3 months
- October 1, 2019: Latest possible start date.

Prior unfunded applicants may reapply, but all applications will be treated as new submissions. More than one application may be submitted from a single institution, but final funding decisions will take into account a preference to limit multiple awards to one institution.

An applicant may not apply for, use, or accept funds for a research project or part of a project already supported by funds from another public or private source. Accordingly, full disclosure of all available and pending funds for research support must be made in the grant application. If funds from other sources become available during the review or tenure of the Junior Investigator Research Award, the applicant/recipient must inform AES in writing so that a decision can be made about continuation of the award.

Applicants may request a delay in the start date of up to 3 months.

More grant information:


Research recommendations:

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Link for LOIs and for full proposals:

For technical difficulties with proposalCENTRAL, please contact their help desk at or 1-800-875-2562 (toll-free US & Canada).

For questions about your application and the review process, contact Susan Fargo:

Executive Office
135 South LaSalle Street
Suite 2850
Chicago, IL 60603

URL for Full Text (RFP):

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